Analytical chemistry relies massively on solvents, which are generally petroleum-based and have hazardous effects. The ideal alternative solvents suitable for analysis should have high selectivity, solvency, low toxicity, and low environmental impacts, be easily biodegradable and recyclable, and be obtained from renewable resources at a reasonable price. Obviously, finding the ideal solvent that meets all the aforementioned requirements is a big challenge. Therefore, the selection of the optimum solvent will always be a compromise depending on the extraction procedure, the analytical method, the matrix, and the target molecules. In this current opinion, we provide an instantaneous picture of current knowledge on alternative and sustainable solvents used in analytical laboratories either for sample preparation or analysis in terms of innovation and development of safe products and procedures.

分析化学很大程度上依赖于溶剂，这些溶剂通常是石油基的并且具有危险作用。适用于分析的理想替代溶剂应具有较高的选择性，溶解性，低毒性和对环境的影响，易于生物降解和再循环，并以合理的价格从可再生资源中获得。显然，找到满足上述所有要求的理想溶剂是一项巨大的挑战。因此，取决于萃取程序，分析方法，基质和目标分子，最佳溶剂的选择将始终是一个折衷方案。根据目前的观点，