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Inflammaging: Blame the sons. Relationships between the number of sons and the level of inflammatory mediators among post-reproductive women
American Journal of Physical Anthropology ( IF 2.6 ) Pub Date : 2021-04-30 , DOI: 10.1002/ajpa.24295
Andrzej Galbarczyk 1 , Magdalena Klimek 1 , Mateusz Blukacz 1, 2 , Ilona Nenko 1 , Magdalena Jabłońska 1 , Grazyna Jasienska 1
Affiliation  

Reproduction is costly, but sons and daughters differently influence maternal physiology, also in older age. In particular, having sons may negatively influence maternal health and may be associated with a shorter life span of mothers. Sons may also contribute to increased inflammaging, a chronic sub-clinical systemic inflammatory state characterized by elevated levels of serum inflammatory mediators. The aim of this study was to examine the impact of the total number of children, and the number of daughters and sons separately on concentrations of C-reactive protein (CRP), and proinflammatory cytokines such as interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α).

中文翻译:

发炎:责备儿子。生育后妇女儿子数与炎症介质水平的关系

生殖成本高昂,但儿子和女儿对母亲生理的影响不同,年龄较大。特别是,有儿子可能会对产妇健康产生负面影响,并可能与母亲的寿命缩短有关。儿子也可能导致炎症增加,这是一种慢性亚临床全身炎症状态,其特征是血清炎症介质水平升高。本研究的目的是检查儿童总数以及女儿和儿子的数量分别对 C 反应蛋白 (CRP) 和促炎细胞因子 (如白细胞介素 6 (IL-6) 和肿瘤) 浓度的影响。坏死因子-α (TNF-α)。
更新日期:2021-06-25
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