Omega-3 fatty acid (O-3FA) supplementation has garnered interest since cardioprotective properties of dietary fish consumption were observed. In the general population, O-3FA supplementation has not improved cardiovascular outcomes. However, icosapent ethyl, a high-dose, purified form of eicosapentaenoic acid, has demonstrated additive cardioprotection to statins in high-risk patients with elevated triglycerides.

中文翻译：

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Omega-3 脂肪酸补充剂在心血管事件一级和二级预防中的作用：新见解。

自从观察到食用鱼类具有心脏保护作用以来，Omega-3 脂肪酸 (O-3FA) 补充剂引起了人们的兴趣。在一般人群中，补充 O-3FA 并没有改善心血管结局。然而，二十碳五烯酸的高剂量、纯化形式二十碳五烯酸乙酯已被证明对甘油三酯升高的高危患者的他汀类药物具有额外的心脏保护作用。