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Short Communication: Coronavirus Disease 19 Among People Living with HIV in Western India: An Observational Cohort Study
AIDS Research and Human Retroviruses ( IF 1.5 ) Pub Date : 2021-07-22 , DOI: 10.1089/aid.2021.0004
Sanjay Pujari 1, 2 , Sunil Gaikwad 1, 2 , Abhishek Chitalikar 1 , Digamber Dabhade 1 , Kedar Joshi 1 , Vivek Bele 1
Affiliation  

A retrospective cohort study was conducted to assess clinical characteristics and outcomes of coronavirus disease-19 (COVID-19) among people living with HIV (PLHIV) in western India. Out of 86 PLHIV with COVID-19 illness, 19.7% had severe/critical illness and 6 (6.9%) individuals died. Median (interquartile range) age was 51 (47–56) years and 77.6% were male. Eighty-five PLHIV were on antiretroviral treatment with 98% having a viral load <200 copies/mL. Hypertension (HTN) (38.3%) and diabetes mellitus (17.4%) were commonest comorbidities. Fifty-eight percent PLHIV were hospitalized while 6.9% individuals needed intensive care. Presence of medical comorbidity was significantly associated with severe/critical COVID-19, whereas HTN was significantly associated with mortality. Recovery from COVID-19 was documented in 93% PLHIV. In conclusion, PLHIV in western India have similar COVID-19 clinical outcomes as compared with those reported historically among general population. Presence of medical comorbidities rather than HIV-related disease characteristics is associated with severe COVID-19 illness.

中文翻译:

简短交流:印度西部 HIV 感染者中的冠状病毒病 19:一项观察性队列研究

进行了一项回顾性队列研究,以评估印度西部 HIV 感染者 (PLHIV) 中冠状病毒病 19 (COVID-19) 的临床特征和结果。在 86 名患有 COVID-19 疾病的 PLHIV 中,19.7% 患有严重/危重疾病,6 人 (6.9%) 死亡。中位(四分位距)年龄为 51 (47-56) 岁,77.6% 为男性。85 名感染者接受了抗逆转录病毒治疗,其中 98% 的病毒载量 <200 拷贝/毫升。高血压 (HTN) (38.3%) 和糖尿病 (17.4%) 是最常见的合并症。58% 的感染者需要住院治疗,而 6.9% 的人需要重症监护。合并症与严重/危重 COVID-19 显着相关,而 HTN 与死亡率显着相关。93% 的 PLHIV 患者从 COVID-19 中恢复。综上所述,与以往在一般人群中报告的结果相比,印度西部的 PLHIV 具有相似的 COVID-19 临床结果。存在医学合并症而不是 HIV 相关疾病特征与严重的 COVID-19 疾病有关。
更新日期:2021-07-24
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