Objective

Absorption spectroscopy and calorimetry has been a very convenient tool in the diagnosis of a variety of diseases. In recent times, fluorescence emission spectroscopy is proposed to be a more sensitive technique for disease detection.

Methods

In this context, fluorescence emission spectra have been obtained from blood and urine samples from clinically suspected subjects of cancer (N = 40) as compared with normal control samples.

Results

Based on a certain set of fluorometric ratio parameters the samples of suspected subjects were scored positive or negative to assess the validity of the spectral technique in detecting cancer, irrespective of organ or stage. This study was done in the premises of a hospital with the blinded sets of blood and urine samples and it has classified correctly 30 out of 40 (75% true positive) indicating a reasonable level of accuracy of this new, simple technique

Conclusion

It could be of significant value as the first-line defense in the screening process of any cancer.

中文翻译：

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通过血液和尿液的荧光光谱筛查癌症–双盲研究

客观的

吸收光谱法和量热法已经成为诊断各种疾病的非常方便的工具。近年来，荧光发射光谱法被认为是用于疾病检测的更灵敏的技术。

方法

在这种情况下，与正常对照样品相比，从临床上可疑的癌症受试者（N = 40）的血液和尿液样品中获得了荧光发射光谱。

结果

基于一组特定的荧光比率参数，可疑受试者的样本被评定为阳性或阴性，以评估光谱技术在检测癌症中的有效性，而与器官或阶段无关。这项研究是在一家医院中用盲法采集的血液和尿液样本进行的，它已经正确地对40种样本中的30种进行了正确分类（75％的真实阳性），表明这项新的简单技术的准确性水平合理

结论

作为任何癌症筛查过程中的一线防御，它都可能具有重要价值。