Introduction: Vitamin D deficiency is now a well-recognized public health problem affecting almost every second person throughout the world. Recent evidence from many population-based studies has indicated that a poor vitamin D status is a predictor of future strokes. Materials and Methods: We reviewed recent studies on 25-hydroxyvitamin D [25(OH)D] and symptomatic ischemic stroke. A graded increase in the risk of symptomatic ischemic stroke with decreasing levels of plasma 25(OH)D has been found in most of the studies. Vitamin D also has a role in the poststroke period where its deficiency may hinder the rehabilitation process. Conclusions: After reviewing current literature on the subject, we conclude that there are some data to suggest the role of vitamin D in patients with stroke but it cannot be concluded as a risk factor for stroke. Larger population-based studies are needed to confirm the causative role of vitamin D in stroke.


中文翻译：

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维生素D在脑血管疾病中的作用


简介：维生素 D 缺乏症现在是一个公认的公共卫生问题，影响着全世界几乎每一个人。许多基于人群的研究的最新证据表明，维生素 D 状态不佳是未来中风的预测因素。材料和方法：我们回顾了最近关于 25-羟基维生素 D [25(OH)D] 和症状性缺血性卒中的研究。大多数研究发现，随着血浆 25(OH)D 水平的降低，症状性缺血性卒中的风险逐渐增加。维生素 D 在中风后时期也有作用，其缺乏可能会阻碍康复过程。结论：在回顾了有关该主题的当前文献后，我们得出结论，有一些数据表明维生素 D 在中风患者中的作用，但不能将其视为中风的危险因素。需要更大规模的基于人群的研究来证实维生素 D 在中风中的致病作用。