With the advancement of technology and the development of agriculture, the use of pesticides in this industry has also increased. The aim of this study was to investigate the effects of Abamectin toxin on survival and intestinal tissue of Caspian Roach as one of the valuable species in the Caspian Sea. For this purpose, 126 fingerlings fish were exposed to a different level of Abamectin for 96 h. Data analyzed showed that there was a significant correlation between fish mortality rate and Abamectin concentrations. Histological assays showed some typical tissue damages such as vaculation, necrosis, bleeding, epithelial degeneration, the intestinal villi destruction, deformation, and destruction of epithelial cells. Moreover, some clinical signs occurred like increasing operculum movement, swimming near the water surface, anxiety, and death with open mouth. The results of the present study showed that Abamectin can have toxicity effects on Caspian roach, also to sub-lethal concentrations, leading to several tissue damages and reduced survival rate of fish.

Graphical abstract

中文翻译：

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蟑螂（Rutilus rut​​ilus caspicus）对亚致死浓度的阿维菌素暴露的组织病理学评价

随着技术的进步和农业的发展，该行业中农药的使用也增加了。这项研究的目的是调查阿维菌素毒素对里海蟑螂作为里海有价值的物种之一的存活和肠道组织的影响。为此，将126种鱼种鱼暴露于不同水平的阿维菌素中96小时。分析数据表明，鱼类死亡率与阿维菌素浓度之间存在显着相关性。组织学分析显示一些典型的组织损伤，例如排空，坏死，出血，上皮变性，肠绒毛破坏，上皮细胞变形和破坏。此外，还发生了一些临床体征，例如骨运动增加，在水面附近游泳，焦虑，和张开嘴的死亡。本研究的结果表明，阿维菌素对里海蟑螂具有毒性作用，对亚致死浓度也有毒害作用，从而导致多种组织损伤并降低了鱼类的成活率。

图形概要