This study aimed to investigate the specific risk factors for the transmission of novel coronavirus (SARS-CoV-2) among healthcare workers in different campuses of a university hospital and to reveal the risk factors for antibody positivity. In this retrospective cross-sectional study, 2988 (82%) of 3620 healthcare workers in a university hospital participated. The coronavirus disease 2019 (COVID-19) antibody was investigated using serum from healthcare workers who underwent COVID-19 antibody testing. The antibody test results of the participants were evaluated based on their work campus, their profession and their workplace. The statistical significance level was p < 0.05 in all analyses. Of the participants in this study, 108 (3.6%) were antibody positive, and 2880 (96.4%) were negative. Antibody positivity rates were greater in nurses compared with other healthcare workers (p < 0.001). Regarding workplace, antibody positivity was greater in those working in intensive care compared to those working in other locations (p < 0.001). Healthcare workers are at the highest risk of being infected with COVID-19. Those who have a higher risk of infection among healthcare workers and those working in high-risk areas should be vaccinated early and use personal protective equipment during the pandemic. Trial Registration: Retrospective permission was obtained from both the local ethics committee and the Turkish Ministry of Health for this study (IRB No:71522473/050.01.04/370, Date: 05.20.2020).

中文翻译：

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某大学附属医院医护人员预防接种期间新型冠状病毒血清阳性及相关因素的横断面研究


本研究旨在调查某大学医院不同院区医护人员之间传播新型冠状病毒（SARS-CoV-2）的具体危险因素，并揭示抗体阳性的危险因素。在这项回顾性横断面研究中，某大学医院的 3620 名医护人员中有 2988 名 (82%) 参与了这项研究。使用接受过 COVID-19 抗体检测的医护人员的血清对 2019 冠状病毒病 (COVID-19) 抗体进行了研究。参与者的抗体检测结果是根据他们的工作校园、职业和工作场所进行评估的。所有分析中的统计显着性水平均为 p < 0.05。在这项研究的参与者中，108 人（3.6%）抗体呈阳性，2880 人（96.4%）抗体呈阴性。与其他医护人员相比，护士的抗体阳性率更高 (p < 0.001)。关于工作场所，与在其他地方工作的人相比，在重症监护室工作的人的抗体阳性率更高 (p < 0.001)。医护人员感染 COVID-19 的风险最高。医护人员和高风险地区工作人员中感染风险较高的人员，应及早接种疫苗，并在疫情期间使用个人防护用品。试验注册：本研究已获得当地伦理委员会和土耳其卫生部的回顾性许可（IRB 号：71522473/050.01.04/370，日期：2020 年 5 月 20 日）。