Lateralized periodic discharges (LPDs) are a common electroencephalographic (EEG) pattern in the neurointensive care unit setting. LPDs are typically observed in association with acute structural lesions of the brain with different etiologies. There are no reports describing a link between the occurrence of LPDs and the administration of remifentanil. Remifentanil is a rapid-acting pure μ-opioid receptor agonist, which is indicated to provide analgesia and sedation in mechanically ventilated patients in intensive care units. We present a case of an 84-year-old man with neuroglycopenia who developed LPDs while sedated with remifentanil. We report, for the first time, a potential relationship between remifentanil and the induction of LPDs.

侧向周期性放电 (LPD) 是神经重症监护室环境中常见的脑电图 (EEG) 模式。LPD 通常与具有不同病因的大脑急性结构性病变相关联。没有报告描述 LPD 的发生与瑞芬太尼给药之间的联系。瑞芬太尼是一种速效纯μ-阿片受体激动剂，适用于重症监护病房机械通气患者的镇痛和镇静作用。我们报告了一例 84 岁男性神经性糖减少症，他在使用瑞芬太尼镇静时出现 LPD。我们首次报告了瑞芬太尼与 LPD 诱导之间的潜在关系。