Neonatal pertussis has the potential for severe complications, even death. Mothers have been identified as the most frequent source of neonatal pertussis. Almost a dozen countries have implemented pertussis vaccination programs for pregnant women to protect neonates, but Japan has not yet done so. The aim of this questionnaire-based study was to ascertain the willingness of women to be vaccinated during pregnancy and the factors associated with willingness. Subjects were 977 pregnant women who visited either of two selected hospitals for maternity health checks. Most of the women were in their first pregnancy (96%) and about half considered a physician to be the most reliable source of information about vaccination (481/977, 49%). “Willingness to receive pertussis vaccination” was significantly associated with the factors “no fear of receiving vaccination” (odds ratio [OR]=3.10, 95% confidence interval [CI]: 2.21–4.34), “necessary to prevent pertussis” (OR=8.70, 95% CI: 6.17–12.28), “effective in pregnancy”(OR=5.46, 95% CI: 3.94–7.56), and “no concern about side effects after vaccination”(OR=3.03, 95% CI: 1.66–5.55). Pregnant women are likely to consider vaccination if they have a good understanding of the disease and its outcomes. Physicians are well positioned to improve knowledge and attitudes toward pertussis vaccination during pregnancy.

新生儿百日咳有可能导致严重的并发症，甚至死亡。母亲已被确定为新生儿百日咳的最常见来源。近十几个国家已经为孕妇实施了百日咳疫苗接种计划以保护新生儿，但日本尚未这样做。这项基于问卷的研究的目的是确定妇女在怀孕期间接种疫苗的意愿以及与意愿相关的因素。受试者是 977 名前往两家选定医院进行产妇健康检查的孕妇。大多数妇女是第一次怀孕 (96%)，大约一半的妇女认为医生是最可靠的疫苗接种信息来源 (481/977, 49%)。“接种百日咳疫苗的意愿”与“不怕接种疫苗”的因素显着相关（优势比 [OR]=3.10，95% 置信区间 [CI]：2.21–4.34）、“有必要预防百日咳”（OR =8.70, 95% CI: 6.17–12.28)，“怀孕有效”（OR=5.46, 95% CI: 3.94–7.56），“不用担心接种后的副作用”（OR=3.03, 95% CI： 1.66–5.55）。如果孕妇对疾病及其结果有很好的了解，她们可能会考虑接种疫苗。医生有能力在怀孕期间提高对百日咳疫苗接种的知识和态度。和“无需担心接种疫苗后的副作用”（OR=3.03，95% CI：1.66–5.55）。如果孕妇对疾病及其结果有很好的了解，她们可能会考虑接种疫苗。医生有能力在怀孕期间提高对百日咳疫苗接种的知识和态度。和“无需担心接种疫苗后的副作用”（OR=3.03，95% CI：1.66–5.55）。如果孕妇对疾病及其结果有很好的了解，她们可能会考虑接种疫苗。医生有能力在怀孕期间提高对百日咳疫苗接种的知识和态度。