Question There is a large worldwide gap between the service need and provision for mental, neurological and substance use disorders. WHO’s Mental Health Gap Action Programme (mhGAP) intervention guide (IG), provides evidence-based guidance and tools for assessment and integrated management of priority disorders. Our 2017 systematic review identified 33 peer-reviewed studies describing mhGAP-IG implementation in low-income and middle-income countries. Study selection and analysis We searched MEDLINE, Embase, PsycINFO, Web of Knowledge, Scopus, CINAHL, LILACS, ScieELO, Cochrane, PubMed databases, 3ie, Google Scholar and citations of our review, on 24 November 2020. We sought evidence, experience and evaluations of the mhGAP-IG, app or mhGAP Humanitarian IG, from any country, in any language. We extracted data from included papers, but heterogeneity prevented meta-analysis. Findings Of 2621 results, 162 new papers reported applications of the mhGAP-IG. They described mhGAP training courses (59 references), clinical applications (n=49), research uses (n=27), contextual adaptations (n=13), economic studies (n=7) and other educational applications (n=7). Most were conducted in the African region (40%) and South-East Asia (25%). Studies demonstrated improved knowledge, attitudes and confidence post-training and improved symptoms and engagement with care, post-implementation. Research studies compared mhGAP-IG-enhanced usual care with task-shared psychological interventions and adaptation studies optimised mhGAP-IG implementation for different contexts. Economic studies calculated human resource requirements of scaling up mhGAP-IG implementation and other educational studies explored its potential for repurposing. Conclusions The diverse, expanding global mhGAP-IG literature demonstrates substantial impact on training, patient care, research and practice. Priorities for future research should be less-studied regions, severe mental illness and contextual adaptation of brief psychological interventions. Data sharing is not applicable as no datasets were generated and/or analysed for this study. The data analysed in this systematic review came from publications of research studies whose data may be sought by direct contact with the study authors.

中文翻译：

---

世卫组织心理健康差距行动计划（mhGAP）干预指南：更新的证据和影响系统审查


问题 全球范围内对精神、神经和物质使用障碍的服务需求和提供之间存在巨大差距。世卫组织的心理健康差距行动计划（mhGAP）干预指南（IG）为重点疾病的评估和综合管理提供了循证指导和工具。我们 2017 年的系统审查确定了 33 项同行评审研究，描述了低收入和中等收入国家的 mhGAP-IG 实施情况。研究选择和分析 我们于 2020 年 11 月 24 日检索了 MEDLINE、Embase、PsycINFO、Web of Knowledge、Scopus、CINAHL、LILACS、ScieELO、Cochrane、PubMed 数据库、3ie、Google Scholar 以及我们综述的引用。我们寻求证据、经验和分析。来自任何国家、以任何语言对 mhGAP-IG、应用程序或 mhGAP 人道主义 IG 进行评估。我们从纳入的论文中提取数据，但异质性阻碍了荟萃分析。结果 在 2621 项结果中，162 篇新论文报告了 mhGAP-IG 的应用。他们描述了 mhGAP 培训课程（59 篇参考文献）、临床应用（n=49）、研究用途（n=27）、情境适应（n=13）、经济研究（n=7）和其他教育应用（n=7） 。大多数是在非洲地区（40%）和东南亚（25%）进行的。研究表明，培训后知识、态度和信心得到改善，症状和护理参与度得到改善。研究将 mhGAP-IG 增强型常规护理与任务共享心理干预进行比较，适应研究优化了针对不同情况的 mhGAP-IG 实施。经济研究计算了扩大 mhGAP-IG 实施的人力资源需求，其他教育研究则探讨了其重新利用的潜力。 结论 多样化、不断扩大的全球 mhGAP-IG 文献表明对培训、患者护理、研究和实践具有重大影响。未来研究的重点应该是研究较少的地区、严重的精神疾病和简短心理干预的情境适应。数据共享不适用，因为本研究没有生成和/或分析数据集。本系统评价中分析的数据来自研究出版物，其数据可通过直接联系研究作者来获取。