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Fatty acid synthesis enables brain metastasis
Nature Cancer ( IF 23.5 ) Pub Date : 2021-04-26 , DOI: 10.1038/s43018-021-00202-y
Felix C E Vogel 1 , Almut Schulze 1
Affiliation  

Cancer cells need to adapt their metabolic state to different microenvironments, particularly during metastatic spread, when they are exposed to the circulatory system as well as the distant organ. Two studies now show that upregulation of fatty acid synthesis is required for the formation of breast cancer metastasis in the lipid-poor environment of the brain.

中文翻译:

脂肪酸合成使脑转移

癌细胞需要使其代谢状态适应不同的微环境,特别是在转移扩散期间,当它们暴露于循环系统以及远处器官时。现在有两项研究表明,在大脑的脂质贫乏环境中,乳腺癌转移的形成需要脂肪酸合成的上调。
更新日期:2021-04-26
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