Recurrent spontaneous abortion (RSA), termed as two or more consecutive pregnancy loss is a great problem for some women of childbearing age. A large number of evidence confirm that there may be an immune background of RSA. As a member of the innate immune system, uterine natural killer (uNK) cells account for about 70% of total lymphocytes during pregnancy and play a critical role in the establishment and maintenance of pregnancy. This review mainly introduces the phenotype, origin, receptor, and function of uNK cells to illuminate its relationship with RSA.

中文翻译：

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子宫自然杀伤细胞和复发性自然流产

复发性自然流产 (RSA)，称为连续两次或更多次流产，对于一些育龄妇女来说是一个大问题。大量证据证实可能存在 RSA 的免疫背景。作为先天免疫系统的一员，子宫自然杀伤（uNK）细胞约占妊娠期淋巴细胞总数的70%，在妊娠的建立和维持中发挥着关键作用。本综述主要介绍了uNK细胞的表型、起源、受体和功能，以阐明其与RSA的关系。