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Development of Pathological Diagnosis Support System Using Micro-computed Tomography
Acta Histochemica et Cytochemica ( IF 1.6 ) Pub Date : 2021-04-28 , DOI: 10.1267/ahc.20-00033
Tomonari Hayakawa 1 , Atsushi Teramoto 1 , Yuka Kiriyama 2 , Tetsuya Tsukamoto 2 , Ayumi Yamada 1 , Kuniaki Saito 1 , Hiroshi Fujita 3
Affiliation  

In pathological diagnosis, the cutting position of pathological materials is subjectively determined by pathologists. This leads to a low cutting accuracy, which in turn may lead to incorrect diagnoses. In this study, we developed a system that supports the determination of the cutting position by visualizing and analyzing the internal structure of pathological material using micro-computed tomography (CT) before cutting. This system consists of a dedicated micro-CT and cutting support software. The micro-CT system has a fixture for fixing the target, enabling the scanning of easily deformable pathological materials. In the cutting support software, a function that interactively selects the extraction plane while displaying the volume rendering image and outputs a pseudo-histological image was implemented. Our results confirmed that the pseudo-histological image showed the fine structure inside the organ and that the latter image was highly consistent with the pathological image.



中文翻译:

微计算机断层扫描技术在病理诊断支持系统中的应用

在病理诊断中,病理材料的切割位置由病理学家主观确定。这导致切割精度低,进而可能导致错误的诊断。在这项研究中,我们开发了一种系统,该系统通过在切割前使用微计算机断层扫描(CT)可视化和分析病理材料的内部结构来支持确定切割位置。该系统由专用的微型CT和切割支持软件组成。微型CT系统具有用于固定目标的固定装置,可扫描易变形的病理材料。在切割支持软件中,实现了在显示体绘制图像的同时交互选择提取平面并输出伪组织图像的功能。

更新日期:2021-04-27
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