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Cytokine Production by Tumor Bioptate at Different Pathological Prognostic Stages in Breast Cancer
Doklady Biochemistry and Biophysics ( IF 0.8 ) Pub Date : 2021-04-24 , DOI: 10.1134/s1607672921020010
A I Autenshlyus 1, 2 , A A Studenikina 1, 2 , N A Varaksin 3 , V V Lyakhovich 2
Affiliation  

Abstract

Differences in the production of cytokines by tumor biopsy specimens were revealed depending on the pathological prognostic stages of The American Joint Committee on Cancer (AJCC) of invasive nonspecific breast carcinoma (INBC). The patients with a predominant absence of metastases in combination with a triple negative molecular subtype differ from the patients with other pathological prognostic stages in the cytokine-producing tumor resource of IL-18, IL-1β, IL-1Ra, TNF-α, GM-CSF, and MCP-1.



中文翻译:

Tumor Bioptate 在乳腺癌不同病理预后阶段产生的细胞因子

摘要

根据美国癌症联合委员会 (AJCC) 的侵袭性非特异性乳腺癌 (INBC) 的病理预后阶段,揭示了肿瘤活检标本产生的细胞因子的差异。在产生细胞因子的肿瘤资源 IL-18、IL-1β、IL-1Ra、TNF-α、GM 中,主要不存在转移且具有三阴性分子亚型的患者与其他病理预后分期的患者不同-CSF 和 MCP-1。

更新日期:2021-04-26
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