With introducing the possibility of early diagnosis through biomarker detection, this method has become important in the field of disease diagnosis. Particle sorting based on conventional digital microfluidics (DMF) mostly employs magnetic beads. In this study, the micropillar-based DMF device confirmed the ability of microbead filtering to detect specific biomarkers. The proposed device was implemented using micro-electromechanical systems, and SU-8 micropillar was realized based on the micro-patterning technology. DMF was able to control droplet movements considering the principle of electrowetting on dielectric. The moving speed of a droplet varied according to the electrode shape and applied voltage. As the droplet moved, the polystyrene bead was sorted corresponding to the interval of the fabricated SU-8 micropillar.

随着通过生物标志物检测引入早期诊断的可能性，该方法在疾病诊断领域变得重要。基于传统数字微流体 (DMF) 的粒子分选主要采用磁珠。在这项研究中，基于微柱的 DMF 设备证实了微珠过滤检测特定生物标志物的能力。所提出的装置是使用微机电系统实现的，SU-8 微柱是基于微图案技术实现的。考虑到电介质上的电润湿原理，DMF 能够控制液滴运动。液滴的移动速度根据电极形状和施加的电压而变化。随着液滴的移动，聚苯乙烯珠被分类为与制造的 SU-8 微柱的间隔相对应。