ABSTRACT

Background: Food is already recognized as a trigger for migraine, but its mechanism of action has not been fully clarified. There is evidence that they act on the pathogenesis of migraine, interfering with meningeal inflammation, vasodilation and cerebral glucose metabolism.

Aim: The aim of this study was to know which plant foods are triggers for migraine and the latency time for the onset of pain.

Method: We interviewed patients with migraine and tension-type headache about plant foods that trigger headache and onset time of the headache. We studied 3,935 migraine patients and 1,163 with tension-type headache.

Results: There were headaches triggered by plant foods after 90.5 ± 7.9 minutes of ingestion in 40.3% (1,584/3,935) of migraine patients and none with tension-type headache. Headaches triggered by plant foods intake are distributed in the following order of frequency: watermelon (29.5%), passion fruit (3.73%), orange (2.01%), pineapple (1.52%), grape (0.51%), banana (0.46%), cucumber (0.43%), acerola (0.25%) and papaya (0.25%).

Conclusions: Many plant foods, especially watermelon, may trigger headache attacks in migraine patients within a few minutes.

摘要

背景：食物已被认为是偏头痛的诱因，但其作用机制尚未完全阐明。有证据表明它们作用于偏头痛的发病机制，干扰脑膜炎症、血管舒张和脑糖代谢。

目的：这项研究的目的是了解哪些植物性食物是偏头痛的诱因以及疼痛发作的潜伏期。

方法: 我们采访了偏头痛和紧张型头痛患者，了解引发头痛的植物性食物和头痛的发作时间。我们研究了 3,935 名偏头痛患者和 1,163 名紧张型头痛患者。

结果： 40.3% (1,584/3,935) 的偏头痛患者在摄入植物性食物 90.5 ± 7.9 分钟后出现头痛，而没有出现紧张型头痛。摄入植物性食物引发的头痛按以下频率顺序分布：西瓜（29.5%）、百香果（3.73%）、橙子（2.01%）、菠萝（1.52%）、葡萄（0.51%）、香蕉（0.46%） )、黄瓜 (0.43%)、针叶樱桃 (0.25%) 和木瓜 (0.25%)。

结论：许多植物性食物，尤其是西瓜，可能会在几分钟内引发偏头痛患者的头痛发作。