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In vitro bioactivity and antibacterial performances of atmospheric plasma sprayed c-axis preferential oriented hydroxyapatite coatings
Surface & Coatings Technology ( IF 5.3 ) Pub Date : 2021-04-23 , DOI: 10.1016/j.surfcoat.2021.127209
Xiaomei Liu , Dingyong He , Zheng Zhou , Xingye Guo , Yi Liu , Wenjia Hou , Hua Li

Atmospheric plasma spraying (APS) is widely used in the fabrication of hydroxyapatite (HA) coating due to the advantages of low-cost, simple operation and it can be used to fabricate coatings with controllable structure. Despite all these advantages, the application of APS deposited HA coating for long-term use is limited by its low crystallinity, low phase purity and poor antibacterial property efficiency. Herein, HA coatings with high crystallinity, phase purity and c-axis crystalline orientation were fabricated by APS. In vitro cell, culture testing suggested that the c-axis oriented HA coating was more effective to promote the proliferation of osteoblasts cells compared with other coatings. The antibacterial activity of HA coating against the bacteria indicated that the c-axis oriented HA coating restrained the bacterial adhesion, and the antibacterial effect of the E. coli bacteria was more pronounced than that of the S. epidermidis bacteria. This study suggests that the HA coatings with the specific c-axis crystalline orientation are available for their potential applications for orthopedic and dental implantation.



中文翻译:

大气等离子喷涂c轴优先取向羟基磷灰石涂层的体外生物活性和抗菌性能

大气等离子喷涂(APS)由于具有成本低廉,操作简单的优点而被广泛用于羟基磷灰石(HA)涂层的制造,并且可用于制造结构可控的涂层。尽管具有所有这些优点,但是由于其低结晶度,低相纯度和较差的抗菌性能,限制了APS沉积HA涂层的长期使用。本文中,通过APS制备了具有高结晶度,相纯度和c轴晶体取向的HA涂层。体外细胞,培养测试建议Ç轴取向的HA涂层比其他涂层更有效地促进成骨细胞的增殖。HA涂层对细菌的抗菌活性表明c轴取向的HA涂层抑制了细菌的粘附,并抑制了E的抗菌作用。大肠杆菌S.细菌更为明显。表皮细菌。这项研究表明,具有特定c轴晶体取向的HA涂层可用于其在整形外科和牙科植入中的潜在应用。

更新日期:2021-04-27
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