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Short time effect of Covid 19 pandemic on HbA1c and acute metabolic complications in children with type 1 diabetes
medRxiv - Endocrinology Pub Date : 2021-04-22 , DOI: 10.1101/2021.04.18.21255687
Ilknur Arslanoglu , Figen Akcali , Fatma Yavuzyilmaz , Mehmet Ali Sungur

Background COVID19 pandemic is currently affecting every aspect of daily life of communitiesy throughout the world. We aimed to check how this situation affects the metabolic control of children with type 1 diabetes. Methods We analyzed all patients with type 1 diabetes a HbA1c test after at least two months ensuing the start of the epidemic in Turkey. We compared the results with the most recent HbA1c test in the hospitals automation system before the epidemic. In addition, diabetic ketoacidosis (DKA) and severe hypoglycemia rates were compared. Results Among the eligible 219 cases 77.6% had decreased HbA1c levels according to their former result. Mean drop was about 9.71% compared to the former test in the whole group. Age, sex and time interval between two tests were not found to affect this tendency. Diabetic ketoacidosis rate was the same as before the pandemic, whereas severe hypoglycemia rates increased. Conclusions Despite the potential of the pandemic to affect routine care of chronic diseases in a negative way the short term metabolic control of type 1 children with type 1 diabetes improved. Telemedicine support by the diabetes team and increased care in the family environment might be possible explanations.

中文翻译:

Covid 19大流行对1型糖尿病儿童HbA1c和急性代谢并发症的短期影响

背景COVID19大流行目前正在影响世界各地社区日常生活的方方面面。我们旨在检查这种情况如何影响1型糖尿病儿童的代谢控制。方法在土耳其疫情爆发至少两个月后,我们对所有1型糖尿病患者进行了HbA1c测试分析。我们将结果与流行前医院自动化系统中最新的HbA1c测试进行了比较。此外,比较了糖尿病酮症酸中毒(DKA)和严重的低血糖发生率。结果符合条件的219例患者中,有77.6%的HbA1c水平根据其先前的结果下降。在整个组中,与之前的测试相比,平均下降约为9.71%。没有发现两次测试之间的年龄,性别和时间间隔会影响这种趋势。糖尿病酮症酸中毒发生率与大流行前相同,而严重的低血糖发生率增加。结论尽管大流行可能会对慢性病的常规护理产生负面影响,但对1型1型糖尿病儿童的短期代谢控制有所改善。糖尿病团队的远程医疗支持和家庭环境中更多的照护可能是可能的解释。
更新日期:2021-04-23
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