Effectiveness of Metformin for Weight Reduction in Children and Adolescents Treated with Mixed Dopamine and Serotonin Receptor Antagonists: A Naturalistic Cohort Study,Journal of Child and Adolescent Psychopharmacology

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Effectiveness of Metformin for Weight Reduction in Children and Adolescents Treated with Mixed Dopamine and Serotonin Receptor Antagonists: A Naturalistic Cohort Study
Journal of Child and Adolescent Psychopharmacology ( IF 1.5 ) Pub Date : 2021-06-16 , DOI: 10.1089/cap.2021.0006
Yael Levy-Shraga _{1,

2} , Lee Rima Madi ₂ , Mor Shalev ₃ , Kineret Mazor-Aronovitch _{1,

2} , Maya Schwartz-Lifshitz _{2,

3} , Doron Gothelf _{2,

3,

4}

Affiliation

Objectives: Mixed dopamine and serotonin receptor antagonists (DSRAs) are associated with significant weight gain and its complications. Our aim was to evaluate the effectiveness of metformin in reducing body mass index (BMI) and metabolic parameters in children treated with DSRAs.

中文翻译：

二甲双胍对使用混合多巴胺和血清素受体拮抗剂治疗的儿童和青少年体重减轻的有效性：一项自然队列研究

目标：混合多巴胺和血清素受体拮抗剂 (DSRA) 与显着的体重增加及其并发症有关。我们的目的是评估二甲双胍在降低接受 DSRA 治疗的儿童的体重指数 (BMI) 和代谢参数方面的有效性。

更新日期：2021-06-18

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