Progress in [18F]Fluorination by Using Aryliodonium(III) Compounds and Application for PET Tracer Syntheses,Mini-Reviews in Organic Chemistry

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Progress in [18F]Fluorination by Using Aryliodonium(III) Compounds and Application for PET Tracer Syntheses
Mini-Reviews in Organic Chemistry ( IF 1.9 ) Pub Date : 2021-02-28 , DOI: 10.2174/1570193x17999200629155733
Kotaro Kikushima ₁ , Ravi Kumar ₂ , Toshifumi Dohi ₁

Affiliation

[¹⁸F]-labeled drugs and radioligands are most frequently used in positron-emission tomography (PET) radiopharmaceuticals for both clinical and preclinical research. Various methods for the introduction of [¹⁸F]fluorine into complex molecules through fluorination reactions have been reported. Herein, recent advances in [¹⁸F]-fluorination utilizing aryliodonium(III) compounds are highlighted.

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