Objective:

To assess thermal-sensory thresholds and psychosocial factors in children with Complex Regional Pain Syndrome Type 1 (CRPS-I) compared to healthy children.

Methods:

We conducted quantitative sensory testing on 34 children with CRPS-I and 56 pain-free children. Warm, cool, heat, and cold stimuli were applied to the forearm. Children with CRPS-I had the protocol administered to the pain site and the contralateral-pain site. Participants completed the self-report Behavior Assessment System for Children.

Results:

Longer pain durations (>5.1 months) were associated with decreased sensitivity to cold pain on the pain site (P = .04). Higher pain-intensity ratings were associated with elevated anxiety scores (P = .03). Anxiety and social stress were associated with warmth sensitivity (both P < .05) on the contralateral-pain site.

Conclusions:

Pain duration is an important factor in assessing pediatric CRPS-I. Hyposensitivity in the affected limb may emerge due to degeneration of nociceptive nerves. Anxiety may contribute to thermal-sensory perception in childhood CRPS-I.

中文翻译：

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复杂区域疼痛综合征1型儿童的感觉功能和心理因素

客观的：

与健康儿童相比，评估 1 型复杂区域疼痛综合征 (CRPS-I) 儿童的热感觉阈值和心理社会因素。

方法：

我们对 34 名患有 CRPS-I 的儿童和 56 名无痛儿童进行了定量感官测试。对前臂施加暖、冷、热和冷刺激。患有 CRPS-I 的儿童对疼痛部位和对侧疼痛部位进行了治疗。参与者完成了儿童自我报告行为评估系统。

结果：

较长的疼痛持续时间（>5.1 个月）与疼痛部位对冷痛的敏感性降低有关（P = .04）。较高的疼痛强度等级与较高的焦虑评分相关（P = .03）。焦虑和社会压力与对侧疼痛部位的温度敏感性相关（均P < .05）。

结论：

疼痛持续时间是评估儿科 CRPS-I 的重要因素。由于伤害感受神经的退化，可能会出现受影响肢体的低敏感性。焦虑可能有助于儿童 C​​RPS-I 的热感觉感知。