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Alpha particle induced reactions on 151Eu: Possibility of production of 152Tb radioisotope for PET imaging
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms ( IF 1.3 ) Pub Date : 2021-04-21 , DOI: 10.1016/j.nimb.2021.04.007
A.N. Moiseeva , R.A. Aliev , V.N. Unezhev , N.S. Gustova , A.S. Madumarov , N.V. Aksenov , V.A. Zagryadskiy

For the first time, cross sections of the 151Eu(α,xn)155−xTb (x = 2–6) reactions were measured by stack foil technique in the alpha particle range 60 → 19 MeV. Experimental excitation functions were compared with theoretical data from TENDL 2019 library and calculated by EMPIRE-3.2.3 code. Thick target yields for terbium radioisotopes were calculated. The possibility of the practical application of the studied reactions for the production of 152Tb and 149Tb was assessed. It was shown that higher energy of alpha particles is required to produce 149Tb. The production of 152Tb is affected by the influence of side reactions. It is possible to decrease the total content of impurities (153Tb+151Tb) at EOB to 18% of the activity of the 152Tb under 8-hour irradiation by limiting the energy range of incident particles to 42 → 34 MeV. The 152Tb yield will be 222 MBq/μA.



中文翻译:

Alpha粒子在151 Eu上引起的反应:生产152 Tb放射性同位素用于PET成像的可能性

第一次,通过堆叠箔技术在60→19 MeV的α粒子范围内测量了151 Eu(α,x n)155- x Tb(x = 2–6)反应的截面。将实验激励函数与TENDL 2019库中的理论数据进行比较,并通过EMPIRE-3.2.3代码进行计算。计算了radio放射性同位素的目标浓收率。评估了所研究的反应在生产152 Tb和149 Tb中的实际应用的可能性。结果表明,生产149 Tb需要更高的α粒子能量。152的生产Tb受副反应的影响。通过将入射粒子的能量范围限制为42→34 MeV,可以在8小时的照射下将EOB处的杂质总含量(153 Tb + 151 Tb)降至152 Tb活性的18%。在152 Tb的产量将是222活度/μA。

更新日期:2021-04-21
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