Despite significant progress in our understanding and clinical management of multisystem inflammatory syndrome in children (MIS-C), significant challenges remain. Here, we review recently published studies on the clinical diagnosis, risk stratification, and treatment of MIS-C, highlighting key gaps in research progress that are a microcosm for challenges in translational pediatric research. We then discuss potential solutions in the realm of translational bioinformatics.

中文翻译：

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儿童多系统炎症综合征：儿科研究中转化生物信息学的挑战和机遇的缩影。


尽管我们对儿童多系统炎症综合征（MIS-C）的理解和临床管理取得了重大进展，但仍然存在重大挑战。在这里，我们回顾了最近发表的关于 MIS-C 的临床诊断、风险分层和治疗的研究，强调了研究进展中的关键差距，这是转化儿科研究挑战的一个缩影。然后我们讨论转化生物信息学领域的潜在解决方案。