The purpose of this retrospective cohort study was to determine prevalence of sternal lymphadenopathy in a population of dogs undergoing splenectomy, and to evaluate if the prevalence was associated with splenic malignancy. In addition, the study investigated if survival in dogs diagnosed with hemangiosarcoma (HSA) differed between those with or without sternal lymphadenopathy at the time of surgery. Digital radiographs and medical records for dogs who underwent splenectomy from 2013 to 2016 where retrospectively reviewed. One hundred ninety-five dogs underwent splenectomy during the study period. The overall prevalence of sternal lymphadenopathy was 12.8%. The prevalence of sternal lymphadenopathy in dogs with hemangiosarcoma was 16.2% (12/74), other malignancy was 15.8% (3/19), and with a benign process 9.8% (10/102). There was no significant association between sternal lymphadenopathy with hemoperitoneum (p = .20) or between sternal lymphadenopathy and presence of neoplasia (p = .37). There was no significant difference in survival probability in all dogs with or without sternal lymphadenopathy (p = .073). However, sternal lymphadenopathy was associated with lower survival in 74 dogs with HSA (p = .036) and 19 with other splenic malignancies (p = .039). The presence of sternal lymphadenopathy should not be considered a negative prognostic indicator if present in dogs presenting with a hemoperitoneum. Although the presence of sternal lymphadenopathy at the time of initial presentation was not significantly associated with survival time in all dogs with splenic disease, it may have predictive value related to survival of dogs with splenic malignancy.

中文翻译：

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胸骨淋巴结肿大对脾切除犬恶性及生存的预后价值

这项回顾性队列研究的目的是确定接受脾切除术的狗群中胸骨淋巴结病的患病率，并评估患病率是否与脾脏恶性肿瘤相关。此外，该研究调查了诊断为血管肉瘤 (HSA) 的狗在手术时是否存在胸骨淋巴结肿大的存活率是否存在差异。回顾性审查了 2013 年至 2016 年接受脾切除术的狗的数字 X 光片和医疗记录。在研究期间，195 只狗接受了脾切除术。胸骨淋巴结病的总体患病率为 12.8%。血管肉瘤犬胸骨淋巴结病的患病率为 16.2% (12/74)，其他恶性肿瘤为 15.8% (3/19)，良性病变为 9.8% (10/102)。p  = .20) 或在胸骨淋巴结肿大和肿瘤存在之间 ( p  = .37)。在所有患有或不患有胸骨淋巴结肿大的狗中，生存概率没有显着差异（p  = .073）。然而，胸骨淋巴结肿大与 74 只患有 HSA ( p  = .036) 的狗和 19 只患有其他脾脏恶性肿瘤的狗 ( p = .039)。如果出现腹腔积血的狗，胸骨淋巴结肿大不应被视为阴性预后指标。尽管最初出现胸骨淋巴结肿大与所有脾病犬的存活时间没有显着相关性，但它可能对脾脏恶性肿瘤犬的存活率具有预测价值。