Recently, a glovebox breach led to the potential exposure of 15 Los Alamos National Laboratory employees to 238Pu. Given what is known about the material involved in the incident, the possibility of an intake with a ceramic-type component must be considered. Incidents in which intakes of ceramic solubility-type material is suspected represent a challenge for internal dose assessment via urine bioassay because even relatively large doses cannot be detected in urine until many months after the intake. Ideally, in these situations fecal samples should be collected to assess the intake, but in this case fecal sampling was delayed. This paper presents a method to calculate the maximum possible doses for all individuals involved in an incident using only early time-decreasing urine bioassay measurements.

中文翻译：

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摄入可能含有陶瓷类材料成分的一组个体的最大可能剂量。

最近，手套箱破裂导致 15 名洛斯阿拉莫斯国家实验室员工可能接触 238Pu。鉴于对事件中涉及的材料的了解，必须考虑陶瓷类部件摄入的可能性。怀疑摄入陶瓷溶解型材料的事件对通过尿液生物测定进行内部剂量评估构成了挑战，因为即使是相对较大的剂量，也要在摄入后几个月才能在尿液中检测到。理想情况下，在这些情况下应收集粪便样本来评估摄入量，但在这种情况下，粪便采样被推迟。本文提出了一种仅使用早期随时间减少的尿液生物测定测量值来计算事件涉及的所有个体的最大可能剂量的方法。