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Perforated High-Grade Mixed Neuroendocrine Nonneuroendocrine Neoplasm of Cecum: Unusual Presentation of Rare Disease
Gastrointestinal Tumors ( IF 0.8 ) Pub Date : 2021-04-20 , DOI: 10.1159/000512237
Gunasekaran Gopalakrishnan 1 , Bheemanathi Hanuman Srinivas 2 , Biju Pottakkat 1 , Senthil Gnanasekaran 1 , Raja Kalayarasan 1
Affiliation  

Mixed neuroendocrine nonneuroendocrine neoplasms (MiNENs) are rare neoplasms of the gastrointestinal tract, where the neuroendocrine as well as the nonneuroendocrine components each comprise at least 30% of the tumor. Of all cases of colorectal malignancies, MiNENs constitute around 3–9.6%, with only a few cases reported to be arising in the cecum. Since majority present with nonspecific clinical and radiological findings, its diagnosis preoperatively is almost impossible and these are usually diagnosed after histopathological examination of the resected specimen. Owing to the rarity of these tumors as well as lack of complete molecular characterization, optimal treatment remains unestablished. We, here, report a rare case of MiNENs of the cecum infiltrating the right psoas muscle and presenting with perforation for which right hemicolectomy and en bloc excision of the involved psoas muscle was done followed by adjuvant chemotherapy.
Gastrointest Tumors


中文翻译:

盲肠穿孔高级混合神经内分泌非神经内分泌肿瘤:罕见疾病的罕见表现

混合神经内分泌非神经内分泌肿瘤(MiNENs)是胃肠道的罕见肿瘤,其中神经内分泌以及非神经内分泌成分各占肿瘤的至少30%。在所有大肠恶性肿瘤病例中,MiNENs约占3–9.6%,据报道只有少数病例起源于盲肠。由于大多数患者表现出非特异性的临床和放射学发现,因此几乎不可能在术前进行诊断,这些通常是在对切除标本进行组织病理学检查后才诊断出来的。由于这些肿瘤的稀有性以及缺乏完整的分子特征,因此尚无最佳治疗方法。我们在这里
胃肠道肿瘤
更新日期:2021-04-20
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