Considering the Job Demands-Resources (JD-R) model, this study investigated the relation between job demands, job resources and turnover intention among persons with multiple sclerosis (pwMS) as an example of chronic disease. We hypothesized that job demands and job resources are related to turnover intention, as mediated by work engagement, burnout, and MS-related work difficulties. Moreover, we assumed that MS-related work difficulties mediate the relationship between job demands/job resources and burnout and between job resources and work engagement. Using cross-sectional data (N = 360) of pwMS from the Swiss MS Registry, structural equation modelling was applied. The results confirm the JD-R model can be related to turnover intention among pwMS. Moreover, MS-related work difficulties mediated the relationship between job demands and burnout, between job resources and work engagement, and between job resources and burnout. The findings suggest that there may be benefit in applying and adapting the JD-R model for people with a chronic disease such as MS. This group of people might benefit from the promotion of job resources and a reduction in job demands, leading to changes in work engagement, burnout, and MS-related work difficulties and thus to an increased likelihood to stay at work.

中文翻译：

---

慢性病工作需求-资源与离职意愿的关系——以多发性硬化症为例

考虑到工作需求-资源 (JD-R) 模型，本研究调查了多发性硬化症 (pwMS) 作为慢性病患者的工作需求、工作资源和离职意愿之间的关系。我们假设工作需求和工作资源与离职意向有关，通过工作投入、倦怠和 MS 相关的工作困难来调节。此外，我们假设与 MS 相关的工作困难介导了工作需求/工作资源与倦怠之间的关系以及工作资源与工作投入之间的关系。使用横截面数据 ( N = 360) 来自 Swiss MS Registry 的 pwMS，应用了结构方程模型。结果证实 JD-R 模型可以与 pwMS 之间的离职意愿相关。此外，与 MS 相关的工作困难在工作需求与倦怠之间、工作资源与工作投入之间以及工作资源与倦怠之间起中介作用。研究结果表明，应用和调整 JD-R 模型可能对患有 MS 等慢性病的人有益。这群人可能会受益于工作资源的提升和工作需求的减少，导致工作投入、倦怠和 MS 相关工作困难的变化，从而增加留在工作岗位的可能性。