ABSTRACT

Background: Though much research has been done on the cognitive profiles of children, the abilities of patients with SBM as they age into adulthood are not well understood.

Objective: Determine if adults with SBM have impairments in overall cognition, attention, executive function, and memory compared to typically developing adults or a standardized population mean.

Methods: A medical librarian composed a search of spina bifida, adults, and cognitive function. 549 results were screened using title and abstract. Data were extracted using Covidence review software, including risk of bias assessments. 24 studies were included.

Results: Memory impairments, notably working and prospective, have been reported. Results in other domains varied. Average VIQ or PIQ did not imply lack of impairment in other specific domains.

Conclusion: Memory impairments should be accounted for and neuropsychological testing should be considered when providing care to adults with SBM. Future longitudinal cognitive aging and interventional studies are needed.

摘要

背景：尽管对儿童的认知特征进行了大量研究，但人们对 SBM 患者随着年龄的增长进入成年期的能力尚不清楚。

目标：确定与正常发育的成年人或标准化的人口平均值相比，患有 SBM 的成年人在整体认知、注意力、执行功能和记忆力方面是否存在损害。

方法：医学图书馆员对脊柱裂、成人和认知功能进行了搜索。使用标题和摘要筛选了 549 个结果。使用 Covidence 审查软件提取数据，包括偏倚风险评估。纳入了 24 项研究。

结果：已报告记忆障碍，尤其是工作和预期障碍。其他领域的结果各不相同。平均 VIQ 或 PIQ 并不意味着在其他特定领域没有损伤。

结论：在为患有 SBM 的成人提供护理时，应考虑记忆障碍并考虑神经心理学测试。需要未来的纵向认知老化和干预研究。