Psychiatric disorders in individuals with co-occurring autism spectrum disorders (ASD) and intellectual disability (ID) are common, but diagnosis presents many challenges. The Psychopathology in Autism checklist (PAC) is among the very few instruments specifically developed for this group of individuals. The psychometric properties of the PAC (i.e. criterion validity, specificity, sensitivity and predictive values) were explored by comparing scores with assessments on the Aberrant Behavior Checklist (ABC) and examining how well assessment by the PAC at referral predicts final clinical diagnoses. Results indicated a significant correlation with the ABC, further supporting the validity of the PAC. Sensitivity and Specificity for specific diagnoses were variable, although positive predictive value for “any diagnosis’ was relatively high. The study confirms the potential value of the PAC as a screening checklist but highlights the need for clinical diagnosis to be based on a multimodal, multidisciplinary assessment.

同时患有自闭症谱系障碍 (ASD) 和智力障碍 (ID) 的个体的精神疾病很常见，但诊断存在许多挑战。自闭症精神病理学检查表 (PAC) 是专门为这一群体开发的极少数工具之一。通过将分数与异常行为检查表 (ABC) 上的评估进行比较，并检查转诊时 PAC 的评估对最终临床诊断的预测效果，探讨了 PAC 的心理测量特性（即标准有效性、特异性、敏感性和预测值）。结果表明与 ABC 显着相关，进一步支持 PAC 的有效性。尽管“任何诊断”的阳性预测值相对较高，但特定诊断的敏感性和特异性各不相同。该研究证实了 PAC 作为筛查清单的潜在价值，但强调临床诊断需要基于多模式、多学科评估。