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More Than Just Closed and Open: Unraveling a Mechanosensor
Trends in Biochemical Sciences ( IF 11.6 ) Pub Date : 2021-04-17 , DOI: 10.1016/j.tibs.2021.04.002
Vanessa J Flegler 1 , Tim Rasmussen 1 , Bettina Böttcher 1
Affiliation  

The bacterial mechanosensitive channel of small conductance (MscS) is a well-studied model of how mechanical forces from the membrane can be sensed by an embedded protein. A recent study by Zhang et al. visualizes how MscS behaves under membrane tension, entering a desensitized state when it loses all coordinated lipids.



中文翻译:

不仅仅是封闭和开放:解开机械传感器

小电导的细菌机械敏感通道 (MscS) 是一个经过充分研究的模型,研究了嵌入的蛋白质如何感知来自膜的机械力。Zhang等人最近的一项研究。可视化 MscS 在膜张力下的行为,当它失去所有协调的脂质时进入脱敏状态。

更新日期:2021-04-17
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