Adolescence is a period in which eating disorders and juvenile systemic lupus erythematosus are typically diagnosed. The coexistence of both disorders prompts the search for a common aetiology.

In this paper, we present a case of a 16-year-old girl with life-threatening anorexia nervosa followed by clinical and immunological manifestations of systemic lupus erythematosus. The severity of the symptoms of anorexia nervosa resulted in significant delay in proper diagnosis of the concomitant systemic disease which had already been active. The administration of immunosuppressive treatment resulted in decreased lupus activity and resolution of the symptoms of anorexia nervosa. Being affected by one severe and chronic disease does not preclude the coexistence of another disease of different aetiology. However, such coexistence may suggest a common pathophysiology. Many authors have indicated a possible link between anorexia nervosa and many autoimmune disorders. Currently, modern genetic techniques have confirmed a significant correlation between these disorders. This issue needs further investigation and may be helpful in arriving at the final diagnosis in similar cases.

中文翻译：

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一名16岁女性患者的神经性厌食症和红斑性青少年狼疮-常见疾病的起源还是随机的巧合？

青春期是典型的饮食失调和青少年系统性红斑狼疮的时期。两种疾病的共存促使人们寻找共同的病因。

在本文中，我们介绍了一个16岁女孩，危及生命的神经性厌食症，随后出现系统性红斑狼疮的临床和免疫学表现。神经性厌食症状的严重程度导致对已经活跃的伴随系统疾病的正确诊断显着延迟。免疫抑制治疗的给药导致狼疮活性降低和神经性厌食症状的缓解。受一种严重和慢性疾病的影响并不排除另一种病因不同的疾病并存。然而，这种共存可能暗示着共同的病理生理。许多作者指出神经性厌食症与许多自身免疫性疾病之间可能存在联系。现在，现代遗传技术已经证实了这些疾病之间的显着相关性。该问题需要进一步调查，可能有助于在类似情况下做出最终诊断。