Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis,ACS Pharmacology & Translational Science

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Identification of Novel MicroRNAs Targeting SARS-CoV-2 through the Regulation of TMPRSS2/PI3K/AKT/PTEN Alignment in Lung Cancer: An in Silico Analysis
ACS Pharmacology & Translational Science ( IF 4.9 ) Pub Date : 2021-04-16 , DOI: 10.1021/acsptsci.1c00040
Debasmita Mukhopadhyay ₁ , Nour AlSawaftah ₁ , Ghaleb A Husseini ₁

Affiliation

In this study, we investigated the interactions between SARS-CoV-2 and miRNAs associated with lung cancer using bioinformatic approaches. A special focus was placed on TMPRSS2 and lung cancer progression pathways involving AKT/PI3K/PTEN genes.

中文翻译：

通过调节肺癌中的 TMPRSS2/PI3K/AKT/PTEN 比对鉴定靶向 SARS-CoV-2 的新型微 RNA：计算机分析

在这项研究中，我们使用生物信息学方法研究了 SARS-CoV-2 和与肺癌相关的 miRNA 之间的相互作用。特别关注 TMPRSS2 和涉及 AKT/PI3K/PTEN 基因的肺癌进展途径。

更新日期：2021-06-11

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