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Endothelial Cells Differentiated from Porcine Epiblast Stem Cells
Cellular Reprogramming ( IF 1.2 ) Pub Date : 2021-04-16 , DOI: 10.1089/cell.2020.0088
Soo-Been Jeon 1 , Bo-Gyeong Seo 2, 3 , Sang-Ki Baek 1, 4 , Hyeon-Geun Lee 1, 5 , Joon-Hong Shin 1 , In-Won Lee 1 , Hyo-Jin Kim 2, 3 , Sun Young Moon 2, 3 , Keum-Chul Shin 5, 6 , Jung-Woo Choi 5 , Tae-Suk Kim 1, 7 , Joon-Hee Lee 1, 8 , Cheol Hwangbo 2, 3
Affiliation  

Pluripotent stem cells (PSCs) have the ability of self-renewal that can retain the characteristics of the mother cell, and of pluripotency that can differentiate into several body types. PSCs typically include embryonic stem cells (ESCs) derived from the inner cell mass of the preimplantation embryo, and epiblast stem cells (EpiSCs) derived from the epiblast of postimplantation embryo. Although PSCs are able to be used by differentiation into endothelial cells as a potential treatment for vascular diseases, human ESCs and induced PSCs (iPSCs) are followed by ethical and safety issues.

中文翻译:

从猪外胚层干细胞分化而来的内皮细胞

多能干细胞(PSCs)具有自我更新的能力,可以保留母细胞的特性,并具有可以分化成多种体型的多能性。PSCs 通常包括源自植入前胚胎内细胞团的胚胎干细胞 (ESCs) 和源自植入后胚胎外胚层的外胚层干细胞 (EpiSCs)。虽然 PSCs 能够通过分化为内皮细胞作为血管疾病的潜在治疗方法,但人类 ESCs 和诱导的 PSCs (iPSCs) 紧随其后的是伦理和安全问题。
更新日期:2021-04-18
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