Campylobacter fetus fetus (Cff) is a major infectious cause of abortion in sheep worldwide, and an opportunistic human pathogen. Information on Cff as an ovine abortifacient in South America is limited. We describe a case of abortion caused by a multidrug resistant strain of Cff in a sheep in Uruguay. In August 2017, 3/57 pregnant ewes (5.3%) aborted whithin one week. Histopathologic examination of the placenta of an aborted ewe revealed severe neutrophilic and fibrinonecrotizing placentitis with vasculitis and thrombosis of the chorionic arterioles. Cff was isolated on microaerobic culture in Skirrow agar, and further confirmed by 16S rDNA PCR amplification and sequencing, and endpoint and real time PCR assays. Antimicrobial sensitivity testing revealed resistance to tetracyclines, nalidixic acid, telithromycin and clindamycin. Other abortifacients were not detected. Further studies are necessary to determine the geographic distribution, ecology, epidemiology, economic impact, and antimicrobial resistance of Cff in sheep flocks in Uruguay.

胎儿弯曲杆菌( Cff ) 是世界范围内绵羊流产的主要传染性原因，也是一种机会性人类病原体。关于Cff作为南美洲绵羊堕胎药的信息有限。我们描述了乌拉圭一头绵羊中由多重耐药Cff菌株引起的流产病例。2017 年 8 月，3/57 怀孕母羊 (5.3%) 在一周内流产。流产母羊胎盘的组织病理学检查显示严重的中性粒细胞和纤维蛋白坏死性胎盘炎伴血管炎和绒毛膜小动脉血栓形成。Cff在 Skirrow 琼脂微需氧培养中分离，并通过 16S rDNA PCR 扩增和测序以及终点和实时 PCR 测定进一步证实。抗菌药物敏感性测试显示对四环素、萘啶酸、泰利霉素和克林霉素耐药。未检测到其他堕胎药。需要进一步的研究来确定乌拉圭羊群中Cff的地理分布、生态学、流行病学、经济影响和抗菌素耐药性。