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Novel mouse model expands potential human α-cell research
Islets ( IF 1.9 ) Pub Date : 2021-04-14 , DOI: 10.1080/19382014.2021.1914507
Theodore Dos Santos 1, 2 , Patrick E MacDonald 1, 2
Affiliation  

ABSTRACT

A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses— providing an unprecedented resource in human α-cell and diabetes research



中文翻译:

新型小鼠模型扩展了潜在的人类 α 细胞研究

摘要

保留 GLP-1 和 GLP-2 分泌的胰高血糖素敲除小鼠可以改进对移植人胰岛和胰高血糖素反应的研究——为人类 α 细胞和糖尿病研究提供前所未有的资源

更新日期:2021-04-14
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