The International Society on Thrombosis and Hemostasis bleeding assessment tool (ISTH-BAT) was developed to record bleeding symptoms and aid in patient diagnosis. This study was done to investigate the utility of ISTH-BAT in patients suspected to have inherited bleeding disorders. This cross-sectional study was conducted in a tertiary care hospital in Southern India over 3 and 1/2 years. A trained investigator administered the ISTH-BAT questionnaire to 432 patients undergoing evaluation for inherited bleeding disorder prior to routine coagulation screening and confirmatory tests and to 131 healthy volunteers as controls. Among patients, 42(9.7%) had primary hemostatic defect, 150(34.7%) had secondary hemostatic defects and 229(53%) had normal screening coagulogram with mean bleeding scores (BS) being 5.9, 6.9, and 4.2 respectively and the proportion of patients with abnormal BS being 69%, 88.7% and 59.4% respectively; the latter qualifying as unknown hemostatic defect. 11(2.5%) with acquired hemostatic defect on workup were excluded. The mean BS was 1.52 among healthy volunteers. Common bleeding patterns were epistaxis (73.8%), cutaneous bleeding (52.4%), hematuria (54.8%), menorrhagia (50%) in primary hemostatic defect; cutaneous bleeding (72%), muscle hematoma (58.7%), hemarthrosis (46.7%), menorrhagia (58.7%) in secondary hemostatic defects and epistaxis (45.9%), cutaneous bleeding (62.4%), menorrhagia (30.7%) in normal screening coagulogram group. Grade of bleeding was mostly 2 and sometimes 4 in primary, 2–4 in secondary and 1–2 in normal screening coagulogram group. ISTH-BAT is a valuable tool to record lifelong bleeding history. The pattern and score give clues regarding the nature and severity of the bleeding disorder.

国际血栓形成和止血协会出血评估工具 (ISTH-BAT) 的开发是为了记录出血症状并帮助患者诊断。本研究旨在调查 ISTH-BAT 在疑似遗传性出血性疾病患者中的效用。这项横断面研究在印度南部的一家三级医院进行，历时 3 又 1/2 年。一名训练有素的研究人员对 432 名在常规凝血筛查和确认测试之前接受遗传性出血性疾病评估的患者和 131 名作为对照的健康志愿者进行了 ISTH-BAT 问卷调查。患者中，42 例（9.7%）存在原发性止血缺陷，150 例（34.7%）存在继发性止血缺陷，229 例（53%）筛查凝血图正常，平均出血评分（BS）分别为 5.9、6.9 和 4。2，BS异常的患者比例分别为69%、88.7%和59.4%；后者符合未知的止血缺陷。11 例 (2.5%) 在检查时有获得性止血缺陷被排除在外。健康志愿者的平均 BS 为 1.52。原发性止血缺损常见的出血形态有鼻衄（73.8%）、皮肤出血（52.4%）、血尿（54.8%）、月经过多（50%）；皮肤出血 (72%)、肌肉血肿 (58.7%)、关节积血 (46.7%)、继发性止血缺陷中的月经过多 (58.7%) 和鼻衄 (45.9%)、皮肤出血 (62.4%)、月经过多 (30.7%) 正常筛查凝血图组。出血等级主要为 2 级，有时一级为 4 级，二级为 2-4 级，正常筛查凝血图组为 1-2 级。ISTH-BAT 是记录终生出血史的宝贵工具。