Background: Excess body weight (EBW), defined as a body mass index (BMI) ≥25 kg/m², has become the second most important as well as a potentially modifiable risk factor for cancer in many industrialized countries. The more excess weight people have, the higher the risk of certain cancers. Over the past several decades, EBW has been increasing globally not only among adults, but also among children and adolescents. Summary: EBW is causally associated with colorectal, esophageal (adenocarcinoma), gastric (cardia), pancreatic, biliary and hepatocellular cancer. EBW when combined with tobacco smoking, risky alcohol use, or diabetes can act synergistically to cause gastrointestinal cancer. In recent years, more and more young adults (20–40 years old) were diagnosed with EBW-associated neoplasms. People with EBW should be encouraged to join cancer screening programs. Key Messages: Keeping a healthy weight is a major public health concern and reduces the risk of cancer.
Visc Med

中文翻译：

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超重和胃肠道癌风险

背景：超重 (EBW) 定义为体重指数 (BMI) ≥25 kg/m ²，已成为许多工业化国家中第二重要的癌症风险因素，也是一个潜在可改变的风险因素。人们的超重越多，患某些癌症的风险就越高。在过去的几十年中，EBW 在全球范围内不仅在成人中增加，而且在儿童和青少年中也不断增加。概括：EBW 与结直肠癌、食道癌（腺癌）、胃癌（贲门癌）、胰腺癌、胆管癌和肝细胞癌有因果关系。EBW 与吸烟、高风险饮酒或糖尿病相结合可协同作用导致胃肠道癌。近年来，越来越多的年轻人（20-40 岁）被诊断出患有 EBW 相关肿瘤。应鼓励 EBW 患者加入癌症筛查项目。关键信息：保持健康体重是一项重大的公共卫生问题，可降低患癌症的风险。
粘性医学