Chromatomembrane process represents a universal approach to the separation of compounds in liquid–gas and liquid-liquid phases systems. However, the broad application of chromatomembrane separation methods in chemical analysis is restricted by the absence of serially produced chromatomembrane flow cells and the difficulties of their laboratory production. The present work addresses the preparation of chromatomembrane flow cell by using 3D printing. Fused deposition modeling and stereolithography were modes for the production of the flow cell using acrylonitrile-butadiene-styrene and polyacrylate-based Anycubic UV resins respectively. The separation and analytical performance of the 3D-printed flow cell were compared with a polyimide unit fabricated by a milling machine, the trial addressing the determination of phenol in the air. The method is based on chromatomembrane absorption of the analytes in 95 μL of the aqueous phase positioned in the cell. Reversed-phase HPLC with fluorimetric detection was applied for the determination of the absorbed analytes. The detection limit of phenols (phenol and m-cresol) in the air was 0.9 μg/m³ by absorption preconcentration time of 10 min. The volumetric flow rate of the analyzed air through the chromatomembrane cell using an electrodriven aspirator was 0.1 L/min.

中文翻译：

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使用新型 3D 打印微流通池对酚类进行色谱膜预浓缩，然后进行反相 HPLC 测定

层析膜工艺代表了一种在液-气和液-液相系统中分离化合物的通用方法。然而，色谱膜分离方法在化学分析中的广泛应用受到缺乏连续生产的色谱膜流通池及其实验室生产困难的限制。目前的工作解决了使用 3D 打印制备色谱膜流动池的问题。熔融沉积建模和立体光刻是分别使用丙烯腈-丁二烯-苯乙烯和基于聚丙烯酸酯的 Anycubic UV 树脂生产流动池的模式。将 3D 打印流通池的分离和分析性能与由铣床制造的聚酰亚胺单元进行了比较，该试验解决了空气中苯酚的测定问题。该方法基于分析物在位于池中的 95 μL 水相中的色谱膜吸收。具有荧光检测的反相 HPLC 用于测定吸收的分析物。酚类的检出限（苯酚和 通过10分钟的吸收预浓缩时间，空气中的m-甲酚)为0.9μg/m ³。使用电动抽吸器通过色谱膜室的分析空气的体积流速为 0.1 L/min。