A Systematic Review and Meta-Analysis of Risk Factors Associated with Severity and Death in COVID-19 Patients,Canadian Journal of Infectious Diseases and Medical Microbiology

当前位置： X-MOL 学术 › Can. J. Infect. Dis. Med. Microbiol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A Systematic Review and Meta-Analysis of Risk Factors Associated with Severity and Death in COVID-19 Patients
Canadian Journal of Infectious Diseases and Medical Microbiology ( IF 2.6 ) Pub Date : 2021-04-12 , DOI: 10.1155/2021/6660930
Pengqiang Du ₁ , Dandan Li ₂ , Aifeng Wang ₁ , Su Shen ₂ , Zhichao Ma ₃ , Xingang Li ₂

Affiliation

This meta-analysis aims to screen the risk factors for severe illness and death and provide help for early clinical treatment of the new coronavirus (COVID-19). Based on a comprehensive search of PubMed, Embase, and Web of Science databases, we included studies that explored the cause and risk factors for severe illness and death in COVID-19 patients. We evaluated the strength of this relationship using odds ratios (ORs) with 95% confidence intervals (CIs). A total of 17 articles were included; 16 of the 17 articles were from China, and the risk factors associated with severe illness and death were age, sex, and multiple comorbidities. Advanced age (≥65 years, severe illness, OR = 2.62; death, OR = 6.00), male (severe illness, OR = 1.49; death, OR = 1.54), chronic respiratory diseases (severe illness, OR = 5.67; death, OR = 3.72), diabetes (severe illness, OR = 3.27; death, OR = 2.60), hypertension (severe illness, OR = 3.08; death, OR = 3.53), chronic kidney disease (severe illness, OR = 3.59; death, OR = 5.38), and cardiovascular diseases (severe illness, OR = 3.87; death, OR = 4.91) were all risk factors. For COVID-19 patients, advanced age, male, and patients with chronic disease are at higher risk of developing severe illness or even death.

更新日期：2021-04-12

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文