Background Limited information exists regarding the clinical characteristics, management practices, and outcomes of pediatric patients with liver injury in Japan. The aim of this study is to evaluate the characteristics, management, and outcome of pediatric patients with liver injury in Japan. Methods We conducted a multicenter, retrospective cohort study using data from the Japan Trauma Data Bank between 2004 and 2018. Pediatric patients with liver injury were classified into the following management groups: nonoperative management (NOM); NOM with angioembolization (AE); operative management (OM). The primary outcome was in-hospital survival, and the secondary outcomes were dispositions, hospital length of stay (LOS), and rate of discharge to home. Results There were 308 pediatric patients with severe liver injury (organ injury scale grades ≥Ⅲ) during the study period; 135 patients had isolated liver injury and 173 patients had non-isolated liver injury. The rates of NOM, NOM with AE, and OM among all patients were 65%, 23%, and 12%, respectively. AE was highly used both in patients with isolated liver injury (27%) and non-isolated liver injury (22%). In-hospital survival of patients with isolated liver injury and those with non-isolated liver injury were 99% and 88%, respectively. Regarding secondary outcomes among patients with isolated liver injury, 82% were admitted to the intensive care unit. LOS was 11 (8–14) days and 82% were discharged to home. Conclusions Our retrospective observational study showed that management of pediatric patients with severe liver injury in Japan was characterized by high utilization of AE. The in-hospital survival rate in Japan was comparable with that of other developed countries. Data are available on reasonable request.

中文翻译：

---

日本外伤登记处儿科患者的严重肝外伤

背景 关于日本肝损伤儿科患者的临床特征、管理实践和结果的信息有限。本研究的目的是评估日本肝损伤儿科患者的特征、管理和结果。方 NOM 与血管栓塞 (AE)；运营管理（OM）。主要结果是院内生存率，次要结果是处置、住院时间 (LOS) 和出院回家率。结果 研究期间共有重度肝损伤（器官损伤量表分级≥Ⅲ级）患儿308例；135例患者为孤立性肝损伤，173例患者为非孤立性肝损伤。所有患者的 NOM、NOM 伴 AE 和 OM 的发生率分别为 65%、23% 和 12%。AE 在孤立性肝损伤 (27%) 和非孤立性肝损伤 (22%) 患者中使用率很高。孤立性肝损伤和非孤立性肝损伤患者的院内生存率分别为 99% 和 88%。关于孤立性肝损伤患者的次要结局，82% 的患者被送入重症监护病房。LOS 为 11 (8–14) 天，82% 的患者出院回家。结论 我们的回顾性观察研究表明，日本严重肝损伤儿科患者的管理特点是 AE 的高利用率。日本的住院生存率与其他发达国家相当。可应合理要求提供数据。