To further reduce the energy consumption, investment and operation cost of the distillation process, DWC-B and FTCDC are used to strengthen the separation process of ibuprofen sodium mother liquor. Based on the process simulation results, thermodynamic efficiency, economic and environmental impact assessment were carried out and compared with the benchmarked CTCD process. DWC-B and FTCDC have obvious advantages in economy, energy saving and environmental impact. Compared with the benchmarked CTCD process, the FTCDC process is more attractive economically, and its total annual cost is reduced by about 7.83%. The thermodynamic efficiency of DWC-B is 17.62%, and the CO2 emission is reduced by 11.39%. Compared with the benchmarked CTCD process, DWC-B and FTCDC have the advantages of high thermodynamic efficiency, low economic cost and low CO2 emission with a great industrial application prospect.

为了进一步降低蒸馏过程的能耗，投资和运行成本，DWC-B和FTCDC用于加强布洛芬钠母液的分离过程。根据过程模拟结果，进行了热力学效率，经济和环境影响评估，并将其与基准CTCD过程进行了比较。DWC-B和FTCDC在经济，节能和环境影响方面具有明显的优势。与基准的CDCD流程相比，FTCDC流程在经济上更具吸引力，其年度总成本降低了约7.83％。DWC-B的热力学效率为17.62％，CO2排放减少了11.39％。与基准的CDCD工艺相比，DWC-B和FTCDC具有热力学效率高，