Introduction: As part of scaling up the response to the opioid overdose epidemic, there is an opportunity to examine how state public health departments addressed workforce and other infrastructure needs to implement a large-scale opioid overdose prevention program. Understanding how this was done—and any lessons learned from the process—can inform future workforce development and capital improvement efforts. Methods: Administrative data from the Centers for Disease Control and Prevention (CDC) Prescription Drug Overdose Prevention for States (PfS) program were analyzed to understand how states adapted to this emerging public health priority. Results: Six months into the first year of funding, 6 of the 16 state health departments had filled all anticipated staffing positions. States faced challenges obtaining timely expenditure authority and hiring staff. However, states were able to overcome these challenges by strategically reassigning staff, hiring from within, and utilizing existing contract mechanisms. Conclusion: Our analysis revealed how planning, using existing infrastructure, and maintaining a prepared workforce are critical to ensure that public health agencies have the ability to surge to meet emerging challenges and effectively utilize resources to achieve program goals. practical applications: Greater attention should be directed toward strategically addressing known barriers and timelines in work plans and budgets during the application and selection process to ensure implementation readiness.

简介：作为扩大应对阿片类药物过量流行病的一部分，我们有机会研究州公共卫生部门如何解决劳动力和其他基础设施需求，以实施大规模的阿片类药物过量预防计划。了解这是如何完成的——以及从该过程中吸取的任何教训——可以为未来的劳动力发展和资本改善工作提供信息。方法：分析来自疾病控制和预防中心 (CDC) 各州处方药过量预防 (PfS) 计划的行政数据，以了解各州如何适应这一新兴的公共卫生优先事项。结果：在资助第一年的六个月后，16 个州卫生部门中的 6 个已经填补了所有预期的人员职位。各国面临着及时获得支出授权和雇用工作人员的挑战。然而，各州能够通过战略性地重新分配员工、从内部招聘和利用现有合同机制来克服这些挑战。结论：我们的分析揭示了规划、使用现有基础设施和维持一支准备就绪的员工队伍对于确保公共卫生机构有能力应对新出现的挑战并有效利用资源实现计划目标至关重要。实际应用：在申请和选择过程中，应更多地关注战略性地解决工作计划和预算中的已知障碍和时间表，以确保实施准备就绪。