Plastic debris is ubiquitous in the marine environment and many of this is polyethylene based plastic bags. Its potential effect on marine organisms is still understudied. Hence, this study determined the histological changes induced in the intestine and liver of the juvenile rabbit fish, Siganus guttatus. S. guttatus (N = 150) were sub chronically exposed to plastic bag debris suspensions (0, 0.01, 0.1, 1.0 and 10 mg L⁻¹) for 10 days. In addition to histological changes, the condition factor (CF) index of the fishes were assessed. Results showed that there was no significant difference in the CF index of the fishes exposed to varying concentrations of plastic suspensions, there was however histological changes in fishes exposed to 10 mg L⁻¹. The histological changes in the intestine were hyperemia, necrosis, goblet cells hyperplasia, and shortening of the villi. Histological changes in the liver were hyperemic blood vessels and vacuolization. Fishes exposed to 10 mg L⁻¹ exhibited a higher proximal, distal, liver and total organ index as compared to those unexposed (p < 0.05).

塑料碎片在海洋环境中无处不在，其中许多是基于聚乙烯的塑料袋。其对海洋生物的潜在影响仍未被研究。因此，本研究确定了在幼兔鱼Siganus guttatus的肠和肝中诱导的组织学变化。将古氏链球菌（N = 150）亚慢性暴露于塑料袋碎片悬浮液（0、0.01、0.1、1.0和10 mg L ^-1）中，持续10天。除了组织学变化之外，还评估了鱼类的条件因子（CF）指数。结果表明，暴露于不同浓度的塑料悬浮液的鱼的CF指数没有显着差异，但是暴露于10 mg L ^-1的鱼的组织学变化。肠道的组织学变化为充血，坏死，杯状细胞增生和绒毛缩短。肝脏的组织学变化是充血血管和空泡化。暴露于10 mg L ^-1的鱼比未暴露的鱼表现出更高的近端，远端，肝脏和总器官指数（p  <0.05）。