As a kind of biocatalyst with high specificity, natural enzymes can be applied in recognition and detection by selective catalysis. However, the high cost and easy inactivation limit their practical applications. Nanozyme is a kind of nanomaterial which can mimic enzyme-like properties via the instinct ability and has the advantages of low cost, stable performance and wide applications. The biomedical detection based on nanozymes with high sensitivity, excellent specificity and low limit of detection is promising. In this paper, several main types of nanozymes were summarized, followed by the introduction of their research progress in biomedical detection. The outlook of nanozymes in biomedical detection was also proposed at the end of this paper.

天然酶作为一种高特异性的生物催化剂，可通过选择性催化应用于识别和检测。然而，高成本和容易失活限制了它们的实际应用。纳米酶是一种可以通过本能模拟酶样性质的纳米材料，具有成本低，性能稳定，应用广泛等优点。具有高灵敏度，优异的特异性和低检测限的基于纳米酶的生物医学检测是有前途的。本文概述了几种主要的纳米酶类型，然后介绍了它们在生物医学检测中的研究进展。本文结尾还提出了纳米酶在生物医学检测中的应用前景。