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Association between Fecal Calprotectin and Mucosal Healing in Pediatric Patients with Crohn's Disease Who Have Achieved Sustained Clinical Remission with Anti-Tumor Necrosis Factor Agents.
Gut and Liver ( IF 3.4 ) Pub Date : 2021-04-09 , DOI: 10.5009/gnl20300
Yoo Min Lee 1 , Sujin Choi 2, 3 , Byung-Ho Choe 2, 3 , Hyo-Jeong Jang 3, 4 , Seung Kim 5 , Hong Koh 5 , Eun Sil Kim 6 , Mi Jin Kim 6 , Yon Ho Choe 6 , Ben Kang 2, 3
Affiliation  

: Although mucosal healing (MH) is acknowledged as the treatment target in the treat-to-target era, there are limitations on repeated endoscopic examinations, especially in pediatric patients. We aimed to investigate whether fecal calprotectin (FC) could serve as a surrogate marker for the assessment of MH in pediatric patients with Crohn's disease (CD) who have achieved sustained clinical remission (CR) while treated with anti-tumor necrosis factor (TNF) agents.

中文翻译:

使用抗肿瘤坏死因子药物获得持续临床缓解的克罗恩病儿科患者粪便钙卫蛋白与黏膜愈合的关系。

: 虽然黏膜愈合 (MH) 被公认为治疗目标时代的治疗目标,但重复内镜检查存在局限性,尤其是在儿科患者中。我们旨在调查粪便钙卫蛋白 (FC) 是否可以作为评估克罗恩病 (CD) 儿科患者 MH 的替代标志物,这些患者在接受抗肿瘤坏死因子 (TNF) 治疗时已达到持续临床缓解 (CR)代理。
更新日期:2021-04-11
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