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mRNA Transport and Local Translation in Glia
Trends in Cell Biology ( IF 13.0 ) Pub Date : 2021-04-08 , DOI: 10.1016/j.tcb.2021.03.006
Lindsey Madsen Meservey 1 , Ved V Topkar 2 , Meng-Meng Fu 3
Affiliation  

Though mRNA transport and local translation are extensively studied in neurons, emerging evidence supports that these cellular processes are also abundant in non-neuronal glial cells. Here, we explore mechanisms of mRNA transport and local translation in oligodendrocytes, astrocytes, microglia, radial glia, and their functions in development, structure, and intercellular interactions.



中文翻译:

神经胶质细胞中的 mRNA 转运和局部翻译

尽管在神经元中广泛研究了 mRNA 转运和局部翻译,但新出现的证据支持这些细胞过程在非神经元胶质细胞中也很丰富。在这里,我们探讨了少突胶质细胞、星形胶质细胞、小胶质细胞、放射状胶质细胞中 mRNA 转运和局部翻译的机制,以及它们在发育、结构和细胞间相互作用中的功能。

更新日期:2021-05-12
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