Hippocampal volume loss in early schizophrenia has been linked with markers of inflammation and oxidative stress, and with less response of negative symptoms. Aripiprazole has been reported to preserve hippocampal volume and to reduce inflammation.

中文翻译：

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阿立哌唑与首发精神分裂症维持治疗期间减少海马萎缩的关联。

早期精神分裂症的海马体积减少与炎症和氧化应激的标志物有关，并且与阴性症状的反应较少有关。据报道，阿立哌唑可以保持海马体积并减少炎症。