Purpose: 

Coronary artery bypass graft (CABG) surgery is an important treatment option in patients with coronary artery disease. Despite its beneficial effects, CABG surgery and its subsequent hospitalization may reduce physical functional capacity in patients, contributing to physical disability. Our objective was to assess the early disabling effects of CABG surgery and its subsequent hospitalization using direct measurements of physical function.

Methods: 

Patients (n = 44) were assessed pre-surgery and at hospital discharge for physical function using the Short Physical Performance Battery (SPPB) and self-reported physical and mental health by questionnaire.

Results: 

The total SPPB score (P < .001) and all of its components (P < .01-.001) decreased markedly following CABG surgery and hospitalization, with greater reductions in total SPPB score (P < .05) and gait speed (P < .01) in patients with higher body mass index. While CABG surgery and hospitalization reduced patient-reported physical function, changes in these indices largely did not correlate with changes in SPPB outcomes.

Conclusion: 

Our results show the early disabling effects of CABG surgery and hospitalization on directly measured physical function, and that patients with higher body mass index had greater reductions. In addition, our results underscore the need to perform direct measurements of physical function to describe reductions in physiological functional capacity. These findings suggest the need for inpatient rehabilitation or early mobility programs to address this decline in physical function.

中文翻译：

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使用直接测量身体功能评估冠状动脉搭桥手术的早期致残效应

目的： 

冠状动脉搭桥术（CABG）手术是冠状动脉疾病患者的重要治疗选择。尽管具有有益的效果，但冠状动脉搭桥手术及其随后的住院治疗可能会降低患者的身体功能能力，导致身体残疾。我们的目标是通过直接测量身体功能来评估 CABG 手术及其随后住院治疗的早期致残影响。

方法： 

患者 (n = 44) 在手术前和出院时使用短期身体表现电池(SPPB)评估身体功能，并通过问卷自我报告身心健康状况。

结果： 

CABG 手术和住院后，SPPB 总分 ( P < .001) 及其所有组成部分 ( P < .01-.001) 显着下降，其中 SPPB 总分 ( P < .05) 和步态速度 ( P < .01) 体重指数较高的患者。虽然 CABG 手术和住院治疗降低了患者报告的身体功能，但这些指数的变化在很大程度上与 SPPB 结果的变化无关。

结论： 

我们的结果表明，CABG 手术和住院治疗对直接测量的身体功能产生早期致残影响，并且体重指数较高的患者的下降幅度更大。此外，我们的结果强调需要对身体功能进行直接测量以描述生理功能能力的降低。这些发现表明需要住院康复或早期活动计划来解决身体功能下降的问题。