Biomaterials containing carbon nanotubes (CNTs) represent a class of composites, which have generally been underexploited in the medical field. However, recognition of the potential utility of this class of composite materials may form the basis to develop new CNT biomaterials for implants and regenerative medicine scaffolds. Nanocomposite coatings containing chitosan matrix (CHI) reinforced with multiwall CNTs and CaHPO₄ (DCPA) were deposited on pure magnesium substrates using a flexible chemical conversion approach. Field emission scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy were applied to characterize the morphological, chemical, and physical changes that occurred in the composite coatings. The in vitro degradation behavior of the composite-coated samples was evaluated using electrochemical impedance spectroscopy in Hank’s solution. Results showed that the tri-phasic composite coating (CHI/CNTs/DCPA) exhibits the highest electrochemical corrosion resistance in comparison with the bi-phasic composite coating (CHI/CNTs and CHI/DCPA) and monophasic CHI-coated magnesium. Potentiodynamic polarization results in Hank’s solution indicate that the corrosion potential of the tri-phasic coated Mg is − 1.5 V, while the corrosion current density reaches 0.36 µA/cm². Functionalization of the Mg surface by activation at 75°C produces a rough surface that triggers a combination of chemical and physical interactions between the three phases and Mg ions present in the reaction medium. The bi-phasic (CHI/CNTS) and tri-phasic (CHI/CNTs/CaHPO₄) composite coatings revealed high antibacterial performance against Staphylococcus aureus. These corrosion results and the successful deposition of CNT-reinforced CHI/DCPA on pure Mg substrate suggest that the conversion coating approach is effective for the production of new composite coatings for either regenerative medicine or functional implants. As such, the present research might lay the groundwork for a new generation of uses for this versatile class of composite coating materials.

包含碳纳米管（CNTs）的生物材料代表了一类复合材料，在医学领域通常未被充分利用。然而，对这类复合材料潜在用途的认识可能构成开发用于植入物和再生医学支架的新型CNT生物材料的基础。包含由多壁CNT和CaHPO ₄增强的壳聚糖基质（CHI）的纳米复合涂料（DCPA）使用灵活的化学转化方法沉积在纯镁基底上。应用场发射扫描电子显微镜，傅立叶变换红外光谱和X射线光电子能谱来表征复合涂层中发生的形态，化学和物理变化。使用Hank溶液中的电化学阻抗谱评估了复合涂层样品的体外降解行为。结果表明，与双相复合涂层（CHI / CNT和CHI / DCPA）和单相CHI涂层镁相比，三相复合涂层（CHI / CNTs / DCPA）表现出最高的耐电化学腐蚀性能。在Hank溶液中的电位动力学极化结果表明，三相包覆的Mg的腐蚀电位为-1.5 V，²。通过在75°C下活化而使Mg表面官能化，会产生粗糙的表面，该表面触发三相之间的化学和物理相互作用以及反应介质中存在的Mg离子。双相（CHI / CNTS）和三相（CHI / CNTs / CaHPO ₄）复合涂层显示出对金黄色葡萄球菌的高抗菌性能。这些腐蚀结果以及碳纳米管增强的CHI / DCPA在纯Mg基底上的成功沉积表明，转化涂层方法可有效用于生产用于再生医学或功能植入物的新型复合涂层。因此，本研究可能为这种多功能复合涂层材料的新一代用途奠定基础。